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Drug Development Strategy

Spectrum Pharmaceuticals acquires, develops and commercializes a broad and diversified portfolio of oncology drug candidates that meet critical health challenges for which there are few other treatment options.

The company's pipeline includes promising early and late-stage drug candidates with unique formulations and mechanisms of action that address the needs of seriously ill patients, such as new treatment regimens for refractory disease.

Spectrum has a broad and diversified portfolio of proprietary drugs in various stages of development in the fields of oncology and urology.

Our lead development drug, EOquin®, a synthetic Bio-reductive prodrug, is being investigated in the treatment of non-invasive bladder cancer. We began two Phase 3 studies in 2007.

Spectrum also has three drugs in the Phase 2 stage of development: Ozarelix, for the treatment of prostate cancer and benign prostatic hypertrophy, Ortataxel, for the treatment of taxane-refractory tumors, and Satraplatin, a Phase 2 oral, anti-cancer drug, being investigated for non-small cell lung cancer (NSCLC).

The Company has three drugs in the Phase 1 stage of development: SPI-1620, an adjunct to chemotherapy, Elsamitrucin, which will target advanced solid tumors and Lucanthone, a chemotherapy sensitizer in the treatment of recurrent, malignant brain tumors.

Other drugs in development include RenaZorb™, used in the treatment of hyperphosphotemia in end stage renal disease (ESRD), and SPI-205 for chemotherapy induced neuropathy.

For detailed information regarding these drugs, please select from the list below.


Imitrex® is a registered trademark of GlaxoSmithKline.

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